WebMOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MOBKL1B stimulates the kinase activity of STK38 and STK38L. WebMob1a MOB kinase activator 1A [ (house mouse)] Gene ID: 232157, updated on 26-Sep-2024 Summary Predicted to enable protein kinase activator activity. Predicted to be involved in hippo signaling and positive regulation of protein phosphorylation. Predicted to be located in cytosol; nucleolus; and nucleoplasm.
Mob1a MGI Mouse Gene Detail - MGI:2442631 - MOB kinase activator 1A
WebMOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MOBKL1B stimulates the kinase activity of STK38 and STK38L. Web22 okt. 2024 · In MOB1A/B-depleted IECs, expression of Wnt target genes were downregulated but Bmp2 and Tgfbr2 were transcriptionally activated with enhanced YAP activity. In in vivo and in vitro experiments with several signaling inhibitors, it has been shown that the BMP inhibitor LDN193189 or TGF-β inhibitor SB431542 had effects on … centralwarehousebar il
Hippo signalling in the liver: role in development ... - Nature
Web1 jun. 2002 · MOB kinase activator-like 1A. Gene. MOB1-A. Status. UniProtKB reviewed (Swiss-Prot) Organism. Medicago sativa subsp. falcata (Sickle medic) (Medicago falcata) ... PTHR22599 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB 1 hit; Pfam. View protein in Pfam; PF03637 Mob1_phocein 1 hit; SMART. View protein in SMART; SM01388 … Web21 jan. 2024 · LATS1 and LATS2, together with the regulatory proteins MOB kinase activators 1A (MOB1A) and MOB1B, phosphorylate yes-associated protein 1 (YAP; homologue to the Drosophila protein Yorkie... WebPharos : Target Details - MOB1A Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data buy low foods boyle